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BMCBI
2006
178views more  BMCBI 2006»
8 years 8 months ago
GOLEM: an interactive graph-based gene-ontology navigation and analysis tool
Background: The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for na...
Rachel S. G. Sealfon, Matthew A. Hibbs, Curtis Hut...
BMCBI
2006
174views more  BMCBI 2006»
8 years 8 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
BMCBI
2006
142views more  BMCBI 2006»
8 years 8 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
BMCBI
2006
147views more  BMCBI 2006»
8 years 8 months ago
Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Alex Lewin, Ian C. Grieve
BMCBI
2006
156views more  BMCBI 2006»
8 years 8 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
BMCBI
2006
130views more  BMCBI 2006»
8 years 8 months ago
Identifying biological concepts from a protein-related corpus with a probabilistic topic model
Background: Biomedical literature, e.g., MEDLINE, contains a wealth of knowledge regarding functions of proteins. Major recurring biological concepts within such text corpora repr...
Bin Zheng, David C. McLean Jr, Xinghua Lu
BMCBI
2006
137views more  BMCBI 2006»
8 years 8 months ago
GOPET: A tool for automated predictions of Gene Ontology terms
Background: Vast progress in sequencing projects has called for annotation on a large scale. A Number of methods have been developed to address this challenging task. These method...
Arunachalam Vinayagam, Coral del Val, Falk Schuber...
BMCBI
2006
169views more  BMCBI 2006»
8 years 8 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
BMCBI
2006
138views more  BMCBI 2006»
8 years 8 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2008
119views more  BMCBI 2008»
8 years 8 months ago
Gene Ontology density estimation and discourse analysis for automatic GeneRiF extraction
Background: This paper describes and evaluates a sentence selection engine that extracts a GeneRiF (Gene Reference into Functions) as defined in ENTREZ-Gene based on a MEDLINE rec...
Julien Gobeill, Imad Tbahriti, Frédé...
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