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RECOMB
2010
Springer
8 years 11 months ago
Consistency of Sequence-Based Gene Clusters
In comparative genomics, various combinatorial models can be used to specify gene clusters — groups of genes that are co-located in a set of genomes. Several approaches have been...
Roland Wittler, Jens Stoye
SAC
2002
ACM
9 years 1 months ago
Short inversions and conserved gene clusters
Two independent sets of recent observations on newly sequenced microbial genomes pertain to the prevalence of short inversion as a gene order rearrangement process and to the lack...
David Sankoff
NAR
2006
81views more  NAR 2006»
9 years 1 months ago
Visualizing syntenic relationships among the hemiascomycetes with the Yeast Gene Order Browser
The Yeast Gene Order Browser (YGOB) is an online tool designed to facilitate the comparative genomic visualization and appraisal of synteny within and between the genomes of seven...
Kevin P. Byrne, Kenneth H. Wolfe
DAM
2008
116views more  DAM 2008»
9 years 1 months ago
Expected number of breakpoints after t random reversals in genomes with duplicate genes
In comparative genomics, one wishes to deduce the evolutionary distance between dierent species by studying their genomes. Using gene order information, we seek the number of time...
Niklas Eriksen
BMCBI
2007
102views more  BMCBI 2007»
9 years 1 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
ALMOB
2008
160views more  ALMOB 2008»
9 years 1 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
9 years 6 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
GCB
2007
Springer
89views Biometrics» more  GCB 2007»
9 years 7 months ago
Expected Gene Order Distances and Model Selection in Bacteria
The most parsimonous distances calculated in pairwise gene order comparisons cannot accurately reflect the true number of events separating two species, unless the number of chan...
Niklas Eriksen
RECOMB
2002
Springer
10 years 1 months ago
Tests for gene clustering
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Dannie Durand, David Sankoff
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