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9 years 7 months ago
Recovering the Tree-Like Trend of Evolution Despite Extensive Lateral Genetic Transfer: A Probabilistic Analysis
Abstract. Lateral gene transfer (LGT) is a common mechanism of nonvertical evolution where genetic material is transferred between two more or less distantly related organisms. It ...
Sebastien Roch, Sagi Snir
10 years 8 months ago
Algorithms for MDC-Based Multi-locus Phylogeny Inference
One of the criteria for inferring a species tree from a collection of gene trees, when gene tree incongruence is assumed to be due to incomplete lineage sorting (ILS), is minimize ...
Yun Yu, Tandy Warnow, Luay Nakhleh
148views more  IANDC 2011»
11 years 11 days ago
Building species trees from larger parts of phylogenomic databases
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Celine Scornavacca, Vincent Berry, Vincent Ranwez
90views more  SIAMCOMP 2000»
11 years 5 months ago
From Gene Trees to Species Trees
This paper studies various algorithmic issues in reconstructing a species tree from gene trees under the duplication and the mutation cost model. This is a fundamental problem in c...
Bin Ma, Ming Li, Louxin Zhang
145views more  JCB 2007»
11 years 5 months ago
Confounding Factors in HGT Detection: Statistical Error, Coalescent Effects, and Multiple Solutions
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). This process has great significance for unde...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
107views more  BMCBI 2006»
11 years 5 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
135views more  BMCBI 2010»
11 years 5 months ago
GIGA: a simple, efficient algorithm for gene tree inference in the genomic age
Background: Phylogenetic relationships between genes are not only of theoretical interest: they enable us to learn about human genes through the experimental work on their relativ...
Paul D. Thomas
118views more  BMCBI 2010»
11 years 5 months ago
Detecting lateral gene transfers by statistical reconciliation of phylogenetic forests
Background: To understand the evolutionary role of Lateral Gene Transfer (LGT), accurate methods are needed to identify transferred genes and infer their timing of acquisition. Ph...
Sophie S. Abby, Eric Tannier, Manolo Gouy, Vincent...
11 years 7 months ago
Automatic genome-wide reconstruction of phylogenetic gene trees
Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...
11 years 11 months ago
RIATA-HGT: A Fast and Accurate Heuristic for Reconstructing Horizontal Gene Transfer
Horizontal gene transfer (HGT) plays a major role in microbial genome diversification, and is claimed to be rampant among various groups of genes in bacteria. Further, HGT is a ma...
Luay Nakhleh, Derek A. Ruths, Li-San Wang