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BMCBI
2005
144views more  BMCBI 2005»
8 years 9 months ago
GeneRank: Using search engine technology for the analysis of microarray experiments
Background: Interpretation of simple microarray experiments is usually based on the fold-change of gene expression between a reference and a "treated" sample where the t...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2005
154views more  BMCBI 2005»
8 years 9 months ago
GObar: A Gene Ontology based analysis and visualization tool for gene sets
Background: Microarray experiments, as well as other genomic analyses, often result in large gene sets containing up to several hundred genes. The biological significance of such ...
Jason S. M. Lee, Gurpreet Katari, Ravi Sachidanand...
BMCBI
2005
124views more  BMCBI 2005»
8 years 9 months ago
ErmineJ: Tool for functional analysis of gene expression data sets
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...
BMCBI
2005
212views more  BMCBI 2005»
8 years 9 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
BMCBI
2005
112views more  BMCBI 2005»
8 years 9 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
BMCBI
2005
103views more  BMCBI 2005»
8 years 9 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate
BMCBI
2005
70views more  BMCBI 2005»
8 years 9 months ago
Integrating alternative splicing detection into gene prediction
Background: Alternative splicing (AS) is now considered as a major actor in transcriptome/ proteome diversity and it cannot be neglected in the annotation process of a new genome....
Sylvain Foissac, Thomas Schiex
BMCBI
2005
121views more  BMCBI 2005»
8 years 9 months ago
Evaluation of gene importance in microarray data based upon probability of selection
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
Li M. Fu, Casey S. Fu-Liu
BMCBI
2005
81views more  BMCBI 2005»
8 years 9 months ago
Evolutionary sequence analysis of complete eukaryote genomes
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
Jaime E. Blair, Prachi Shah, S. Blair Hedges
IPM
2007
123views more  IPM 2007»
8 years 9 months ago
Generating gene summaries from biomedical literature: A study of semi-structured summarization
Most knowledge accumulated through scientific discoveries in genomics and related biomedical disciplines is buried in the vast amount of biomedical literature. Since understandin...
Xu Ling, Jing Jiang, Xin He, Qiaozhu Mei, Chengxia...
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