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CEC
2003
IEEE
13 years 8 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
CMSB
2006
Springer
13 years 8 months ago
Compositional Reachability Analysis of Genetic Networks
Genetic regulatory networks have been modeled as discrete transition systems by many approaches, benefiting from a large number of formal verification algorithms available for the ...
Gregor Gößler
VISUALIZATION
2002
IEEE
13 years 9 months ago
GeneVis: Visualization Tools for Genetic Regulatory Network Dynamics
GeneVis provides a visual environment for exploring the dynamics of genetic regulatory networks. At present time, genetic regulation is the focus of intensive research worldwide, ...
Charles A. H. Baker, M. Sheelagh T. Carpendale, Pr...
PPSN
2004
Springer
13 years 10 months ago
Evolving Genetic Regulatory Networks for Hardware Fault Tolerance
We present a new approach that is able to produce an increased fault tolerance in bio-inspired electronic circuits. To this end, we designed hardwarefriendly genetic regulatory net...
Arne Koopman, Daniel Roggen
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
13 years 10 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
TACAS
2007
Springer
92views Algorithms» more  TACAS 2007»
13 years 10 months ago
Model Checking Liveness Properties of Genetic Regulatory Networks
Abstract. Recent studies have demonstrated the possibility to build genetic regulatory networks that confer a desired behavior to a living organism. However, the design of these ne...
Grégory Batt, Calin Belta, Ron Weiss
ICANN
2007
Springer
13 years 10 months ago
Identifying Binding Sites in Sequential Genomic Data
The identification of cis-regulatory binding sites in DNA is a difficult problem in computational biology. To obtain a full understanding of the complex machinery embodied in genet...
Mark Robinson, Cristina González Castellano...
HYBRID
2007
Springer
13 years 10 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
13 years 10 months ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke
FORMATS
2007
Springer
13 years 10 months ago
On Timed Models of Gene Networks
Abstract. We present a systematic translation from timed models of genetic regulatory networks into products of timed automata to which one can apply verification tools in order l...
Grégory Batt, Ramzi Ben Salah, Oded Maler