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Yi XianfuLecturer
TIJMU
Yi Xianfu
BMCBI
2011
7 years 10 months ago
N-gram analysis of 970 microbial organisms reveals presence of biological language models
Background: It has been suggested previously that genome and proteome sequences show characteristics typical of natural-language texts such as “signature-style” word usage ind...
Hatice U. Osmanbeyoglu, Madhavi Ganapathiraju
BMCBI
2010
122views more  BMCBI 2010»
7 years 10 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
BCB
2010
161views Bioinformatics» more  BCB 2010»
7 years 10 months ago
Genome-wide compatible SNP intervals and their properties
Recent studies suggest that the mammalian genomes can be subdivided in segments within which there is limited haplotype diversity. Understanding the distribution and structure of ...
Jeremy W. Wang, Kyle J. Moore, Qi Zhang, Fernando ...
BMCBI
2010
161views more  BMCBI 2010»
8 years 25 days ago
LTC: a novel algorithm to improve the efficiency of contig assembly for physical mapping in complex genomes
Background: Physical maps are the substrate of genome sequencing and map-based cloning and their construction relies on the accurate assembly of BAC clones into large contigs that...
Zeev Frenkel, Etienne Paux, David I. Mester, Cathe...
BIB
2010
140views more  BIB 2010»
8 years 25 days ago
Next generation sequencing in functional genomics
Genome-wide sequencing has enabled modern biomedical research to relate more and more events in healthy as well as disease-affected cells and tissues to the genomic sequence. Now ...
Thomas Werner
IPPS
2010
IEEE
8 years 1 months ago
pFANGS: Parallel high speed sequence mapping for Next Generation 454-roche Sequencing reads
Millions of DNA sequences (reads) are generated by Next Generation Sequencing machines everyday. There is a need for high performance algorithms to map these sequences to the refer...
Sanchit Misra, Ramanathan Narayanan, Wei-keng Liao...
GCB
2010
Springer
182views Biometrics» more  GCB 2010»
8 years 1 months ago
Repeat-aware Comparative Genome Assembly
: The current high-throughput sequencing technologies produce gigabytes of data even when prokaryotic genomes are processed. In a subsequent assembly phase, the generated overlappi...
Peter Husemann, Jens Stoye
BMCBI
2010
189views more  BMCBI 2010»
8 years 1 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
RECOMB
2010
Springer
8 years 1 months ago
Limited Lifespan of Fragile Regions in Mammalian Evolution
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Althou...
Max A. Alekseyev, Pavel A. Pevzner
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