BMCBI
2005
13 years 4 months ago
2005
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
BMCBI
2005
13 years 4 months ago
2005
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
TCS
2008
13 years 4 months ago
2008
Most genome rearrangements (e.g., reversals and translocations) can be represented as 2-breaks that break a genome at 2 points and glue the resulting fragments in a new order. Mul...
NAR
2008
13 years 4 months ago
2008
The CGView Server generates graphical maps of circular genomes that show sequence features, base composition plots, analysis results and sequence similarity plots. Sequences can b...
NAR
2008
13 years 4 months ago
2008
The Rice Annotation Project Database (RAP-DB) was created to provide the genome sequence assembly of the International Rice Genome Sequencing Project (IRGSP), manually curated ann...
JCB
2006
13 years 4 months ago
2006
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
JCB
2008
13 years 4 months ago
2008
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
BMCBI
2007
13 years 4 months ago
2007
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
BMCBI
2006
13 years 4 months ago
2006
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
BMCBI
2006
13 years 4 months ago
2006
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...