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BMCBI
2008
155views more  BMCBI 2008»
11 years 2 days ago
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...
Kwangmin Choi, Sun Kim
BMCBI
2007
148views more  BMCBI 2007»
11 years 2 days ago
BPhyOG: An interactive server for genome-wide inference of bacterial phylogenies based on overlapping genes
Background: Overlapping genes (OGs) in bacterial genomes are pairs of adjacent genes of which the coding sequences overlap partly or entirely. With the rapid accumulation of seque...
Yingqin Luo, Cong Fu, Da-Yong Zhang, Kui Lin
BMCBI
2010
144views more  BMCBI 2010»
11 years 2 days ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
BMCBI
2007
154views more  BMCBI 2007»
11 years 2 days ago
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Amit U. Sinha, Jaroslaw Meller
BMCBI
2010
95views more  BMCBI 2010»
11 years 2 days ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
BMCBI
2010
94views more  BMCBI 2010»
11 years 2 days ago
A high-throughput pipeline for the design of real-time PCR signatures
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
BMCBI
2010
102views more  BMCBI 2010»
11 years 2 days ago
Missing genes in the annotation of prokaryotic genomes
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
BMCBI
2010
172views more  BMCBI 2010»
11 years 2 days ago
Accessing the SEED genome databases via Web services API: tools for programmers
Background: The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems ...
Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Ol...
BMCBI
2010
138views more  BMCBI 2010»
11 years 2 days ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2010
100views more  BMCBI 2010»
11 years 2 days ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
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