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JCB
2007
58views more  JCB 2007»
13 years 4 months ago
Gene Maps Linearization Using Genomic Rearrangement Distances
Guillaume Blin, Eric Blais, Danny Hermelin, Pierre...
JCB
2007
78views more  JCB 2007»
13 years 4 months ago
Sorting by Reciprocal Translocations via Reversals Theory
The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of genome...
Michal Ozery-Flato, Ron Shamir
JCB
2007
136views more  JCB 2007»
13 years 4 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...
JCB
2007
92views more  JCB 2007»
13 years 4 months ago
Neighbor Joining Algorithms for Inferring Phylogenies via LCA Distances
Reconstructing phylogenetic trees efficiently and accurately from distance estimates is an ongoing challenge in computational biology from both practical and theoretical consider...
Ilan Gronau, Shlomo Moran
JCB
2007
108views more  JCB 2007»
13 years 4 months ago
A Dynamic Programming Approach for Finding Common Patterns in RNAs
We developed a dynamic programming approach of computing common sequence structure patterns among two RNAs given their primary sequences and their secondary structures. Common pat...
Sven Siebert, Rolf Backofen
JCB
2007
130views more  JCB 2007»
13 years 4 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
JCB
2007
94views more  JCB 2007»
13 years 4 months ago
Domain Architecture Comparison for Multidomain Homology Identification
Nan Song, R. D. Sedgewick, Dannie Durand