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JCB
2008
82views more  JCB 2008»
10 years 2 months ago
Determining Nucleolar Association from Sequence by Leveraging Protein-Protein Interactions
Controlled intra-nuclear organisation of proteins is critical for sustaining correct function of the cell. Proteins and RNA are transported by passive diffusion and associate with...
Mikael Bodén, Rohan D. Teasdale
JCB
2008
111views more  JCB 2008»
10 years 3 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
JCB
2008
82views more  JCB 2008»
10 years 4 months ago
Assessing the Exceptionality of Network Motifs
Franck Picard, Jean-Jacques Daudin, Michel Koskas,...
JCB
2008
159views more  JCB 2008»
10 years 4 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther
JCB
2008
75views more  JCB 2008»
10 years 4 months ago
New, Improved, and Practical k-Stem Sequence Similarity Measures for Probe Design
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
Anthony J. Macula, Alexander Schliep, Morgan A. Bi...
JCB
2008
81views more  JCB 2008»
10 years 4 months ago
Estimating the Ancestral Recombinations Graph (ARG) as Compatible Networks of SNP Patterns
Traditionally nonrecombinant genome, i.e., mtDNA or Y chromosome, has been used for phylogeography, notably for ease of analysis. The topology of the phylogeny structure in this c...
Laxmi Parida, Marta Melé, Francesc Calafell...
JCB
2008
75views more  JCB 2008»
10 years 4 months ago
Reconciliation with Non-Binary Species Trees
Benjamin Vernot, Maureen Stolzer, Aiton Goldman, D...
JCB
2008
69views more  JCB 2008»
10 years 4 months ago
Gene Family Evolution by Duplication, Speciation, and Loss
Cedric Chauve, Jean-Philippe Doyon, Nadia El-Mabro...
JCB
2008
81views more  JCB 2008»
10 years 4 months ago
New Constructions of One- and Two-Stage Pooling Designs
The study of gene functions requires a DNA library of high quality, such a library is obtained from a large mount of testing and screening. Pooling design is a very helpful tool f...
Yongxi Cheng, Ding-Zhu Du
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