JCB
2008
13 years 2 months ago
2008
Controlled intra-nuclear organisation of proteins is critical for sustaining correct function of the cell. Proteins and RNA are transported by passive diffusion and associate with...
JCB
2008
13 years 3 months ago
2008
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
JCB
2008
13 years 4 months ago
2008
JCB
2008
13 years 4 months ago
2008
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
JCB
2008
13 years 4 months ago
2008
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...
JCB
2008
13 years 4 months ago
2008
JCB
2008
13 years 4 months ago
2008
Traditionally nonrecombinant genome, i.e., mtDNA or Y chromosome, has been used for phylogeography, notably for ease of analysis. The topology of the phylogeny structure in this c...
JCB
2008
13 years 4 months ago
2008
JCB
2008
13 years 4 months ago
2008
JCB
2008
13 years 4 months ago
2008
The study of gene functions requires a DNA library of high quality, such a library is obtained from a large mount of testing and screening. Pooling design is a very helpful tool f...