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BMCBI
2005
77views more  BMCBI 2005»
10 years 1 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
BMCBI
2005
94views more  BMCBI 2005»
10 years 1 months ago
YANA - a software tool for analyzing flux modes, gene-expression and enzyme activities
Background: A number of algorithms for steady state analysis of metabolic networks have been developed over the years. Of these, Elementary Mode Analysis (EMA) has proven especial...
Roland Schwarz, Patrick Musch, Axel von Kamp, Bern...
BMCBI
2006
103views more  BMCBI 2006»
10 years 1 months ago
Accelerating the reconstruction of genome-scale metabolic networks
Background: The genomic information of a species allows for the genome-scale reconstruction of its metabolic capacity. Such a metabolic reconstruction gives support to metabolic e...
Richard A. Notebaart, Frank H. J. van Enckevort, C...
BMCBI
2006
107views more  BMCBI 2006»
10 years 1 months ago
Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum
Background: Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metab...
Kalyan Gayen, K. V. Venkatesh
BMCBI
2006
143views more  BMCBI 2006»
10 years 1 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2008
119views more  BMCBI 2008»
10 years 1 months ago
On deducing causality in metabolic networks
Background: Metabolic networks present a complex interconnected structure, whose understanding is in general a non-trivial task. Several formal approaches have been developed to s...
Chiara Bodei, Andrea Bracciali, Davide Chiarugi
BMCBI
2007
182views more  BMCBI 2007»
10 years 1 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...
BIB
2010
129views more  BIB 2010»
10 years 1 months ago
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
Peter D. Karp, Suzanne M. Paley, Markus Krummenack...
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
10 years 3 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
CMSB
2003
Springer
10 years 6 months ago
A Method for Estimating Metabolic Fluxes from Incomplete Isotopomer Information
Metabolic flux estimation—the problem of finding out the rates of reactions in metabolic pathways—is an important problem area in the study of metabolism. The most accurate t...
Juho Rousu, Ari Rantanen, Hannu Maaheimo, Esa Pitk...
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