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BMCBI
2011
10 years 8 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
BMCBI
2005
94views more  BMCBI 2005»
11 years 1 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
JIB
2006
102views more  JIB 2006»
11 years 1 months ago
Analysing Microarray Data using the Multi-functional Immune Ontologiser
Gene expression microarrays are a prominent experimental tool in functional genomics allowing researchers to gain a deeper understanding of biological processes. To date, no such ...
Sabah Khalid, Karl Fraser, Mohsin Khan, Ping Wang,...
BMCBI
2006
116views more  BMCBI 2006»
11 years 1 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
BMCBI
2006
126views more  BMCBI 2006»
11 years 1 months ago
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass ge
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
BMCBI
2006
126views more  BMCBI 2006»
11 years 1 months ago
Effect of data normalization on fuzzy clustering of DNA microarray data
Background: Microarray technology has made it possible to simultaneously measure the expression levels of large numbers of genes in a short time. Gene expression data is informati...
Seo Young Kim, Jae Won Lee, Jong Sung Bae
BMCBI
2008
132views more  BMCBI 2008»
11 years 1 months ago
Computational cluster validation for microarray data analysis: experimental assessment of Clest, Consensus Clustering, Figure of
Background: Inferring cluster structure in microarray datasets is a fundamental task for the so-called -omic sciences. It is also a fundamental question in Statistics, Data Analys...
Raffaele Giancarlo, Davide Scaturro, Filippo Utro
BMCBI
2007
120views more  BMCBI 2007»
11 years 1 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
ALMOB
2007
133views more  ALMOB 2007»
11 years 1 months ago
Characteristics of predictor sets found using differential prioritization
Background: Feature selection plays an undeniably important role in classification problems involving high dimensional datasets such as microarray datasets. For filter-based featu...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
IDEAL
2004
Springer
11 years 6 months ago
Visualisation of Distributions and Clusters Using ViSOMs on Gene Expression Data
Microarray datasets are often too large to visualise due to the high dimensionality. The self-organising map has been found useful to analyse massive complex datasets. It can be us...
Swapna Sarvesvaran, Hujun Yin
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