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BMCBI
2008
128views more  BMCBI 2008»
13 years 4 months ago
An efficient visualization tool for the analysis of protein mutation matrices
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
Maria Pamela C. David, Carlo M. Lapid, Vincent Ric...
BMCBI
2008
87views more  BMCBI 2008»
13 years 4 months ago
Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
Salim Bougouffa, Jim Warwicker
BMCBI
2010
136views more  BMCBI 2010»
13 years 4 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2007
117views more  BMCBI 2007»
13 years 4 months ago
DNA-based watermarks using the DNA-Crypt algorithm
Background: The aim of this paper is to demonstrate the application of watermarks based on DNA sequences to identify the unauthorized use of genetically modified organisms (GMOs) ...
Dominik Heider, Angelika Barnekow
BMCBI
2010
113views more  BMCBI 2010»
13 years 4 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2010
117views more  BMCBI 2010»
13 years 4 months ago
Extracting causal relations on HIV drug resistance from literature
Background: In HIV treatment it is critical to have up-to-date resistance data of applicable drugs since HIV has a very high rate of mutation. These data are made available throug...
Quoc-Chinh Bui, Breanndán Ó Nuall&aa...
FMCAD
2008
Springer
13 years 6 months ago
A Theory of Mutations with Applications to Vacuity, Coverage, and Fault Tolerance
The quality of formal specifications and the circuits they are written for can be evaluated through checks such as vacuity and coverage. Both checks involve mutations to the specif...
Orna Kupferman, Wenchao Li, Sanjit A. Seshia
GECCO
2005
Springer
142views Optimization» more  GECCO 2005»
13 years 10 months ago
Genetic programming: parametric analysis of structure altering mutation techniques
We hypothesize that the relationship between parameter settings, speci cally parameters controlling mutation, and performance is non-linear in genetic programs. Genetic programmin...
Alan Piszcz, Terence Soule