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BMCBI
2008
128views more  BMCBI 2008»
11 years 5 months ago
HAPSIMU: a genetic simulation platform for population-based association studies
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
Feng Zhang, Jianfeng Liu, Jie Chen, Hong-Wen Deng
BMCBI
2008
153views more  BMCBI 2008»
11 years 5 months ago
AWclust: point-and-click software for non-parametric population structure analysis
Background: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually ass...
Xiaoyi Gao, Joshua D. Starmer
GECCO
2008
Springer
107views Optimization» more  GECCO 2008»
11 years 6 months ago
The influence of scaling and assortativity on takeover times in scale-free topologies
In evolving systems, the topological characteristics of population structure have a pronounced impact on the rate of spread of advantageous alleles, and therefore affect selective...
Joshua L. Payne, Margaret J. Eppstein
books