NAR
2011
12 years 11 months ago
2011
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposi...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Abstract. Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, ...