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NAR
2007
111views more  NAR 2007»
13 years 4 months ago
Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together
Protein interaction data exists in a number of repositories. Each repository has its own data format, molecule identifier and supplementary information. Michigan Molecular Interac...
Magesh Jayapandian, Adriane Chapman, V. Glenn Tarc...
BMCBI
2004
174views more  BMCBI 2004»
13 years 4 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
BMCBI
2005
126views more  BMCBI 2005»
13 years 4 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...
BMCBI
2005
127views more  BMCBI 2005»
13 years 4 months ago
Are scale-free networks robust to measurement errors?
Background: Many complex random networks have been found to be scale-free. Existing literature on scale-free networks has rarely considered potential false positive and false nega...
Nan Lin, Hongyu Zhao
BMCBI
2005
253views more  BMCBI 2005»
13 years 4 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
NAR
2008
223views more  NAR 2008»
13 years 4 months ago
AtPID: Arabidopsis thaliana protein interactome database - an integrative platform for plant systems biology
Arabidopsis thaliana Protein Interactome Database (AtPID) is an object database that integrates data from several bioinformatics prediction methods and manually collected informat...
Jian Cui, Peng Li, Guang Li, Feng Xu, Chen Zhao, Y...
BMCBI
2007
202views more  BMCBI 2007»
13 years 4 months ago
ProtNet: a tool for stochastic simulations of protein interaction networks dynamics
Background: Protein interactions support cell organization and mediate its response to any specific stimulus. Recent technological advances have produced large data-sets that aim ...
Massimo Bernaschi, Filippo Castiglione, Alessandra...
BMCBI
2006
157views more  BMCBI 2006»
13 years 4 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu
BMCBI
2006
133views more  BMCBI 2006»
13 years 4 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
BMCBI
2006
114views more  BMCBI 2006»
13 years 4 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...