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TCBB
2010
136views more  TCBB 2010»
9 years 12 months ago
Efficient Extraction of Protein-Protein Interactions from Full-Text Articles
—Proteins and their interactions govern virtually all cellular processes, such as regulation, signaling, metabolism, and structure. Most experimental findings pertaining to such ...
Jörg Hakenberg, Robert Leaman, Nguyen Ha Vo, ...
BMCBI
2005
95views more  BMCBI 2005»
10 years 1 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
BMCBI
2007
107views more  BMCBI 2007»
10 years 1 months ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
BMCBI
2007
124views more  BMCBI 2007»
10 years 1 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
EVOW
2008
Springer
10 years 3 months ago
DEEPER: A Full Parsing Based Approach to Protein Relation Extraction
Abstract. Lexical variance in biomedical texts poses a challenge to automatic protein relation mining. We therefore propose a new approach that relies only on more general language...
Timur Fayruzov, Martine De Cock, Chris Cornelis, V...
CP
2005
Springer
10 years 7 months ago
Applying Constraint Programming to Rigid Body Protein Docking
In this paper we show how Constraint Programming (CP) techniques can improve the efficiency and applicability of grid-based algorithms for optimising surface contact between comple...
Ludwig Krippahl, Pedro Barahona
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
10 years 7 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
KDD
2004
ACM
126views Data Mining» more  KDD 2004»
11 years 1 months ago
High-throughput Protein Interactome Data: Minable or Not?
There is an emerging trend in post-genome biology to study the collection of thousands of protein interaction pairs (protein interactome) derived from high-throughput experiments....
Jake Yue Chen, Andrey Y. Sivachenko, Lang Li
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