BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
13 years 4 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
BMCBI
2007
13 years 4 months ago
2007
Background: Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist for the far larger proteome in human. Furt...
BMCBI
2007
13 years 4 months ago
2007
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
BMCBI
2007
13 years 4 months ago
2007
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
BMCBI
2010
13 years 4 months ago
2010
Background: Biological processes in cells are carried out by means of protein-protein interactions. Determining whether a pair of proteins interacts by wet-lab experiments is reso...
BMCBI
2010
13 years 4 months ago
2010
Background: Protein-protein docking for proteins with large conformational changes was analyzed by using interaction fingerprints, one of the scales for measuring similarities amo...
BMCBI
2010
13 years 4 months ago
2010
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
BMCBI
2010
13 years 4 months ago
2010
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
BMCBI
2010
13 years 4 months ago
2010
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
JOBIM
2000
13 years 8 months ago
2000
Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...