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SIGIR
2004
ACM
13 years 9 months ago
Context sensitive vocabulary and its application in protein secondary structure prediction
Protein secondary structure prediction is an important step towards understanding the relation between protein sequence and structure. However, most current prediction methods use...
Yan Liu, Jaime G. Carbonell, Judith Klein-Seethara...
PCI
2005
Springer
13 years 9 months ago
Protein Classification with Multiple Algorithms
Nowadays, the number of protein sequences being stored in central protein databases from labs all over the world is constantly increasing. From these proteins only a fraction has b...
Sotiris Diplaris, Grigorios Tsoumakas, Pericles A....
SAC
2005
ACM
13 years 10 months ago
Comparing approaches to predict transmembrane domains in protein sequences
There are today several systems for predicting transmembrane domains in membrane protein sequences. As they are based on different classifiers as well as different pre- and post-p...
Paul Davidsson, Johan Hagelbäck, Kenny Svenss...
CIBCB
2005
IEEE
13 years 10 months ago
The Homology Kernel: A Biologically Motivated Sequence Embedding into Euclidean Space
— Part of the challenge of modeling protein sequences is their discrete nature. Many of the most powerful statistical and learning techniques are applicable to points in a Euclid...
Eleazar Eskin, Sagi Snir
BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
13 years 10 months ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
13 years 10 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
SP
2008
IEEE
100views Security Privacy» more  SP 2008»
13 years 10 months ago
Towards Practical Privacy for Genomic Computation
Many basic tasks in computational biology involve operations on individual DNA and protein sequences. These sequences, even when anonymized, are vulnerable to re-identification a...
Somesh Jha, Louis Kruger, Vitaly Shmatikov
AINA
2008
IEEE
13 years 10 months ago
Introducing Variable Gap Penalties into Three-Sequence Alignment for Protein Sequences
The common-use gap penalty strategies, constant penalty and affine gap penalty, have been adopted in the traditional three-sequence alignment algorithm which considers the inserti...
Che-Lun Hung, Chun-Yuan Lin, Yeh-Ching Chung, Chua...
SAC
2009
ACM
13 years 11 months ago
A new protein motif extraction framework based on constrained co-clustering
Signal finding (pattern discovery) in biological sequences is a fundamental problem in both computer science and molecular biology. Many approaches have been proposed for extract...
Francesca Cordero, Alessia Visconti, Marco Botta
DCC
2006
IEEE
14 years 3 months ago
On Compressibility of Protein Sequences
We consider the problem of compressibility of protein sequences. Based on an observed genome-scale long-range correlation in concatenated protein sequences from different organism...
Donald A. Adjeroh, Fei Nan