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NAR
2011
298views Computer Vision» more  NAR 2011»
8 years 4 months ago
PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposi...
Amy L. Robertson, Mark A. Bate, Steve G. Androulak...
NAR
2010
107views more  NAR 2010»
8 years 5 months ago
NAPS: a residue-level nucleic acid-binding prediction server
Nucleic acid-binding proteins are involved in a great number of cellular processes. Understanding the mechanisms underlying these proteins first requires the identification of spe...
Matthew B. Carson, Robert E. Langlois, Hui Lu
NAR
2010
117views more  NAR 2010»
8 years 5 months ago
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore
During cell division/mitosis, a specific subset of proteins is spatially and temporally assembled into protein super complexes in three distinct regions, i.e. centrosome/spindle p...
Jian Ren, Zexian Liu, Xinjiao Gao, Changjiang Jin,...
NAR
2010
165views more  NAR 2010»
8 years 5 months ago
PhosPhAt: the Arabidopsis thaliana phosphorylation site database. An update
: Growth and development of plants depends on uptake and assimilation of nutrients. Many assimilation products of macronutrients are not only essential for plant growth but also ha...
Pawel Durek, Robert Schmidt, Joshua L. Heazlewood,...
NAR
2010
122views more  NAR 2010»
8 years 5 months ago
ELM: the status of the 2010 eukaryotic linear motif resource
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes thr...
Cathryn M. Gould, Francesca Diella, Allegra Via, P...
JMLR
2010
136views more  JMLR 2010»
8 years 5 months ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender
BMCBI
2011
8 years 5 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
BMCBI
2011
8 years 5 months ago
Classification of viral zoonosis through receptor pattern analysis
Background: Viral zoonosis, the transmission of a virus from its primary vertebrate reservoir species to humans, requires ubiquitous cellular proteins known as receptor proteins. ...
Se-Eun Bae, Hyeon Seok Son
BMCBI
2011
8 years 5 months ago
Outer membrane proteins can be simply identified using secondary structure element alignment
Background: Outer membrane proteins (OMPs) are frequently found in the outer membranes of gram-negative bacteria, mitochondria and chloroplasts and have been found to play diverse...
Ren-Xiang Yan, Zhen Chen, Ziding Zhang
BMCBI
2011
8 years 5 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...
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