BMCBI
2010
13 years 4 months ago
2010
Background: The reconstruction of protein complexes from the physical interactome of organisms serves as a building block towards understanding the higher level organization of th...
BMCBI
2008
13 years 4 months ago
2008
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
BMCBI
2008
13 years 4 months ago
2008
Background: Discriminating membrane proteins based on their functions is an important task in genome annotation. In this work, we have analyzed the characteristic features of amin...
BMCBI
2008
13 years 4 months ago
2008
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
BMCBI
2007
13 years 4 months ago
2007
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
BMCBI
2008
13 years 4 months ago
2008
Background: Outer membrane proteins (OMPs) perform diverse functional roles in Gramnegative bacteria. Identification of outer membrane proteins is an important task. Results: This...
BMCBI
2010
13 years 4 months ago
2010
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
BMCBI
2007
13 years 4 months ago
2007
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
BMCBI
2007
13 years 4 months ago
2007
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
BMCBI
2008
13 years 4 months ago
2008
Background: In the past decades, various protein subcellular-location (SCL) predictors have been developed. Most of these predictors, like TMHMM 2.0, SignalP 3.0, PrediSi and Phob...