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RECOMB
2003
Springer
9 years 10 months ago
Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals
We propose a framework for modeling sequence motifs based on the maximum entropy principle (MEP). We recommend approximating short sequence motif distributions with the maximum en...
Gene W. Yeo, Christopher B. Burge
RECOMB
2003
Springer
9 years 10 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
RECOMB
2003
Springer
9 years 10 months ago
Combining phylogenetic and hidden Markov models in biosequence analysis
A few models have appeared in recent years that consider not only the way substitutions occur through evolutionary history at each site of a genome, but also the way the process c...
Adam C. Siepel, David Haussler
RECOMB
2003
Springer
9 years 10 months ago
Approximation of protein structure for fast similarity measures
It is shown that structural similarity between proteins can be decided well with much less information than what is used in common similarity measures. The full C representation c...
Fabian Schwarzer, Itay Lotan
RECOMB
2003
Springer
9 years 10 months ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
RECOMB
2003
Springer
9 years 10 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
RECOMB
2003
Springer
9 years 10 months ago
Haplotype reconstruction from SNP alignment
In this paper, we describe a method for statistical reconstruction of haplotypes from a set of aligned SNP fragments. We consider the case of a pair of homologous human chromosome...
Lei Li, Jong Hyun Kim, Michael S. Waterman
RECOMB
2003
Springer
9 years 10 months ago
A complete and effective move set for simplified protein folding
Neal Lesh, Michael Mitzenmacher, Sue Whitesides
RECOMB
2003
Springer
9 years 10 months ago
Joint classifier and feature optimization for cancer diagnosis using gene expression data
Recent research has demonstrated quite convincingly that accurate cancer diagnosis can be achieved by constructing classifiers that are designed to compare the gene expression pro...
Balaji Krishnapuram, Lawrence Carin, Alexander J. ...
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