RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods ...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2break rearrangements represent standard reversals, fusions, ...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Abstract. Side-chain prediction is an important subproblem of the general protein folding problem. Despite much progress in side-chain prediction, performance is far from satisfact...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Currently, large-scale projects are underway to perform whole genome disease association studies. Such studies involve the genotyping of hundreds of thousands of SNP markers. One o...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromere...
RECOMB
2007
Springer
14 years 4 months ago
2007
Springer
Abstract. Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, ...