RECOMB
2010
Springer
13 years 6 months ago
2010
Springer
Abstract. One of the critical stages in drug development is the identification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discove...
RECOMB
2010
Springer
13 years 8 months ago
2010
Springer
Abstract. While the discovery of structural variants in the human population is ongoing, most methods for this task assume that the genome is sequenced to high coverage (e.g. 40x),...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
Abstract. We consider the problem of aligning two metabolic pathways. Unlike traditional approaches, we do not restrict the alignment to one-to-one mappings between the molecules o...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer
Given molecular genetic data from diploid individuals that, at present, reproduce mostly or exclusively asexually without recombination, an important problem in evolutionary biolog...
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer
Clustering methods are a useful and common first step in gene expression studies, but the results may be hard to interpret. We bring in explicitly an indicator of which genes tie ...
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer
Abstract. In this paper, we focus on finding complex annotation patterns representing novel and interesting hypotheses from gene annotation data. We define a generalization of th...
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer
Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
RECOMB
2010
Springer
13 years 11 months ago
2010
Springer