NAR
2011
12 years 7 months ago
2011
The stability, localization and translation rate of mRNAs are regulated by a multitude of RNAbinding proteins (RBPs) that find their targets directly or with the help of guide RNA...
NAR
2011
12 years 7 months ago
2011
AREsite is an online resource for the detailed investigation of AU-rich elements (ARE) in vertebrate mRNA 30 -untranslated regions (UTRs). AREs are one of the most prominent cis-a...
BIOCOMP
2009
13 years 2 months ago
2009
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
BMCBI
2005
13 years 4 months ago
2005
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
BMCBI
2005
13 years 4 months ago
2005
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
BMCBI
2007
13 years 4 months ago
2007
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
BMCBI
2010
13 years 4 months ago
2010
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
PSB
2004
13 years 5 months ago
2004
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
IPPS
2003
IEEE
13 years 9 months ago
2003
IEEE
The detection of regulatory elements from a large set of regulatory regions is a challenging problem in computational genomics. However, computational methods to extract this biol...