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GCB
2009
Springer
196views Biometrics» more  GCB 2009»
13 years 1 months ago
Comparative Generalized Logic Modeling Reveals Differential Gene Interactions during Cell Cycle Exit in Drosophila Wing Developm
Abstract: A comparative interaction detection paradigm is proposed to study the complex gene regulatory networks that control cell proliferation during development. Instead of atte...
Mingzhou Song, Chung-Chien Hong, Yang Zhang, Laura...
BMCBI
2005
178views more  BMCBI 2005»
13 years 3 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
JMLR
2006
103views more  JMLR 2006»
13 years 3 months ago
MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals
In recent years, there has been a growing interest in applying Bayesian networks and their extensions to reconstruct regulatory networks from gene expression data. Since the gene ...
Dana Pe'er, Amos Tanay, Aviv Regev
BMCBI
2006
202views more  BMCBI 2006»
13 years 3 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
BMCBI
2006
181views more  BMCBI 2006»
13 years 3 months ago
The comprehensive updated regulatory network of Escherichia coli K-12
Background: Escherichia coli is the model organism for which our knowledge of its regulatory network is the most extensive. Over the last few years, our project has been collectin...
Heladia Salgado, Alberto Santos-Zavaleta, Socorro ...
CGF
2008
142views more  CGF 2008»
13 years 3 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
BMCBI
2008
129views more  BMCBI 2008»
13 years 3 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
CEC
2007
IEEE
13 years 7 months ago
Emergence of feedback in artificial gene regulatory networks
In this paper, we present a model for simulating the evolution of development together with a method for the analysis of emergence of negative feedback inside the regulatory networ...
Till Steiner, Lisa Schramm, Yaochu Jin, Bernhard S...
GCB
2005
Springer
138views Biometrics» more  GCB 2005»
13 years 9 months ago
Inferring Regulatory Systems with Noisy Pathway Information
: With increasing number of pathways available in public databases, the process of inferring gene regulatory networks becomes more and more feasible. The major problem of most of t...
Christian Spieth, Felix Streichert, Nora Speer, An...
IJCNN
2006
IEEE
13 years 9 months ago
Reconstruction of Gene Regulatory Networks from Temporal Microarray Data Using Pattern Recognition Techniques
- Gene regulatory networks allow us to study and understand genes’ roles in biological processes. Among others, regulatory networks help to identify pathway initiator genes and t...
Azhar Salim, Faramarz Valafar