BMCBI
2006
13 years 4 months ago
2006
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
BMCBI
2006
13 years 4 months ago
2006
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
BIB
2006
13 years 4 months ago
2006
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
BMCBI
2007
13 years 4 months ago
2007
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
BMCBI
2007
13 years 4 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
BMCBI
2007
13 years 4 months ago
2007
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
BMCBI
2008
13 years 4 months ago
2008
Background: With advances in DNA re-sequencing methods and Next-Generation parallel sequencing approaches, there has been a large increase in genomic efforts to define and analyze...
BMCBI
2010
13 years 4 months ago
2010
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
CF
2008
ACM
13 years 6 months ago
2008
ACM
This paper contributes and evaluates a model and a methodology for implementing parallel wavefront algorithms on the Cell Broadband Engine. Wavefront algorithms are vital in sever...
ISMDA
2005
Springer
13 years 10 months ago
2005
Springer
The use of sequence alignments for establishing protein homology relationships has an extensive tradition in the field of bioinformatics, and there is an increasing desire for more...