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BMCBI
2011
12 years 11 months ago
PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...
BMCBI
2005
106views more  BMCBI 2005»
13 years 4 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
TCBB
2008
76views more  TCBB 2008»
13 years 5 months ago
Hadamard Conjugation for the Kimura 3ST Model: Combinatorial Proof Using Path Sets
Under a stochastic model of molecular sequence evolution the probability of each possible pattern of characters is well defined. The Kimura's three-substitution-types (K3ST) m...
Michael D. Hendy, Sagi Snir