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BMCBI
2004
113views more  BMCBI 2004»
13 years 4 months ago
Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sites
Background: Kernel-based learning algorithms are among the most advanced machine learning methods and have been successfully applied to a variety of sequence classification tasks ...
Peter Meinicke, Maike Tech, Burkhard Morgenstern, ...
BMCBI
2004
130views more  BMCBI 2004»
13 years 4 months ago
PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability
Background: Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which th...
Yanlin Huang, David Kowalski
BMCBI
2004
114views more  BMCBI 2004»
13 years 4 months ago
Analysis of superfamily specific profile-profile recognition accuracy
Background: Annotation of sequences that share little similarity to sequences of known function remains a major obstacle in genome annotation. Some of the best methods of detectin...
James A. Casbon, Mansoor A. S. Saqi
BMCBI
2004
102views more  BMCBI 2004»
13 years 4 months ago
Detection of transposable elements by their compositional bias
Background: Transposable elements (TE) are mobile genetic entities present in nearly all genomes. Previous work has shown that TEs tend to have a different nucleotide composition ...
Olivier Andrieu, Anna-Sophie Fiston, Dominique Anx...
JC
2007
65views more  JC 2007»
13 years 4 months ago
Searching for extensible Korobov rules
Extensible lattice sequences have been proposed and studied in [5–7]. For the special case of extensible Korobov sequences, parameters can be found in [6]. The searches made to ...
Hardeep S. Gill, Christiane Lemieux
BMCBI
2005
102views more  BMCBI 2005»
13 years 4 months ago
Genomic multiple sequence alignments: refinement using a genetic algorithm
Background: Genomic sequence data cannot be fully appreciated in isolation. Comparative genomics
Chunlin Wang, Elliot J. Lefkowitz
BMCBI
2005
94views more  BMCBI 2005»
13 years 4 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2005
140views more  BMCBI 2005»
13 years 4 months ago
JACOP: A simple and robust method for the automated classification of protein sequences with modular architecture
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...
Peter Sperisen, Marco Pagni
BMCBI
2005
147views more  BMCBI 2005»
13 years 4 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
BMCBI
2005
150views more  BMCBI 2005»
13 years 4 months ago
Approaching the taxonomic affiliation of unidentified sequences in public databases - an example from the mycorrhizal fungi
Background: During the last few years, DNA sequence analysis has become one of the primary means of taxonomic identification of species, particularly so for species that are minut...
R. Henrik Nilsson, Erik Kristiansson, Martin Ryber...