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BMCBI
2005
93views more  BMCBI 2005»
8 years 11 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
BMCBI
2008
67views more  BMCBI 2008»
9 years 18 hour ago
Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal p
Background: Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated acr...
Khar Heng Choo, Joo Chuan Tong, Shoba Ranganathan
ISMB
1998
9 years 1 months ago
Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
Henrik Nielsen, Anders Krogh
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