BMCBI
2011
12 years 11 months ago
2011
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
BMCBI
2002
13 years 4 months ago
2002
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
IJON
2006
13 years 4 months ago
2006
We introduce a new approach to model the behavior of neuronal signal transduction networks using stochastic differential equations. We present first a mathematical formulation for...
BMCBI
2006
13 years 4 months ago
2006
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
BMCBI
2006
13 years 4 months ago
2006
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
BMCBI
2007
13 years 4 months ago
2007
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
BMCBI
2007
13 years 4 months ago
2007
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
APVIS
2009
13 years 5 months ago
2009
In this paper, we propose a stochastic simulation to model and analyze cellular signal transduction. The high number of objects in a simulation requires advanced visualization tec...
CMSB
2009
Springer
13 years 7 months ago
2009
Springer
In this paper we consider the modeling of a selected portion of signal transduction events involved in the angiogenesis process. The detailed model of this process contains a large...
CIS
2004
Springer
13 years 9 months ago
2004
Springer
The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interfe...