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107views more  INFORMS 2010»
10 years 4 months ago
A Class Representative Model for Pure Parsimony Haplotyping
Haplotyping estimation from aligned Single Nucleotide Polymorphism (SNP) fragments has attracted more and more attention in the recent years due to its importance in analysis of m...
Daniele Catanzaro, Alessandra Godi, Martine Labb&e...
148views more  BMCBI 2004»
10 years 6 months ago
Bioinformatics analysis of SARS coronavirus genome polymorphism
Background: We have compared 38 isolates of the SARS-CoV complete genome. The main goal was twofold: first, to analyze and compare nucleotide sequences and to identify positions o...
Gordana Pavlovic-Lazetic, Nenad S. Mitic, Milos V....
85views more  NAR 2008»
10 years 6 months ago
Panzea: an update on new content and features
Panzea (, the public web site of the project `Molecular and Functional Diversity in the Maize Genome', has expanded over the past two years in data cont...
Payan Canaran, Edward S. Buckler, Jeffrey Glaubitz...
104views more  BMCBI 2007»
10 years 6 months ago
A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
Background: Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoin...
Oscar M. Rueda, Ramón Díaz-Uriarte
95views more  BMCBI 2010»
10 years 6 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
107views more  BMCBI 2010»
10 years 6 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...