BMCBI
2007
13 years 5 months ago
2007
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
BMCBI
2006
13 years 5 months ago
2006
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
13
Voted
BMCBI
2006
13 years 5 months ago
2006
Background: Various software tools are available for the display of pairwise linkage disequilibrium across multiple single nucleotide polymorphisms. The HapMap project also presen...
BMCBI
2006
13 years 5 months ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
BMCBI
2008
13 years 5 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
BMCBI
2008
13 years 5 months ago
2008
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
BMCBI
2008
13 years 5 months ago
2008
Background: There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not account f...
BMCBI
2008
13 years 5 months ago
2008
Background: An important goal of whole-genome studies concerned with single nucleotide polymorphisms (SNPs) is the identification of SNPs associated with a covariate of interest s...
BMCBI
2008
13 years 5 months ago
2008
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
BMCBI
2010
13 years 5 months ago
2010
Background: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, impute...