TCBB
2011
12 years 11 months ago
2011
Galled trees, directed acyclic graphs that model evolutionary histories with isolated hybridization events, have become very popular due to both their biological significance and ...
TCBB
2011
12 years 11 months ago
2011
—In biomedical data, the imbalanced data problem occurs frequently and causes poor prediction performance for minority classes. It is because the trained classifiers are mostly d...
TCBB
2011
12 years 11 months ago
2011
TCBB
2011
12 years 11 months ago
2011
Abstract—Though biomedical research often draws on knowledge from a wide variety of fields, few visualization methods for biomedical data incorporate meaningful cross-database e...
TCBB
2011
12 years 11 months ago
2011
— Probe defects are a major source of noise in gene expression studies. While existing approaches detect noisy probes based on external information such as genomic alignments, we...
TCBB
2011
12 years 11 months ago
2011
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
TCBB
2011
12 years 11 months ago
2011
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
TCBB
2011
12 years 11 months ago
2011
—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
TCBB
2011
12 years 11 months ago
2011
Stochastic models such as hidden Markov models or stochastic context free grammars can fail to return the correct, maximum likelihood solution in the case of semantic ambiguity. T...
TCBB
2011
12 years 11 months ago
2011
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...