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NAR
2016
63views more  NAR 2016»
3 years 8 months ago
rVarBase: an updated database for regulatory features of human variants
We present here the rVarBase database (http://rv. psych.ac.cn), an updated version of the rSNPBase database, to provide reliable and detailed regulatory annotations for known and ...
Liyuan Guo, Yang Du, Susu Qu, Jing Wang 0003
NAR
2016
63views more  NAR 2016»
3 years 8 months ago
KEGG as a reference resource for gene and protein annotation
KEGG (http://www.kegg.jp/ or http://www.genome.jp/ kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data. Mole...
Minoru Kanehisa, Yoko Sato, Masayuki Kawashima, Mi...
NAR
2016
43views more  NAR 2016»
3 years 8 months ago
miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at the post-transcriptional level. This study describes...
Chih-Hung Chou, Nai-Wen Chang, Sirjana Shrestha, S...
NAR
2016
43views more  NAR 2016»
3 years 8 months ago
WormBase 2016: expanding to enable helminth genomic research
WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved ...
Kevin L. Howe, Bruce J. Bolt, Scott Cain, Juancarl...
NAR
2016
41views more  NAR 2016»
3 years 8 months ago
MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
Mitochondria are complex organelles that house essential pathways involved in energy metabolism, ion homeostasis, signalling and apoptosis. To understand mitochondrial pathways in...
Sarah E. Calvo, Karl R. Clauser, Vamsi K. Mootha
NAR
2016
48views more  NAR 2016»
3 years 8 months ago
HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and
More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urge...
Lucas D. Ward, Manolis Kellis
NAR
2016
39views more  NAR 2016»
3 years 8 months ago
BacWGSTdb, a database for genotyping and source tracking bacterial pathogens
Whole genome sequencing has become one of the routine methods in molecular epidemiological practice. In this study, we present BacWGSTdb (http: //bacdb.org/BacWGSTdb), a bacterial...
Zhi Ruan, Ye Feng
NAR
2016
47views more  NAR 2016»
3 years 8 months ago
ccmGDB: a database for cancer cell metabolism genes
Accumulating evidence has demonstrated that rewiring of metabolism in cells is an important hallmark of cancer. The percentage of patients killed by metabolic disorder has been es...
Pora Kim, Feixiong Cheng, Junfei Zhao, Zhongming Z...
NAR
2016
40views more  NAR 2016»
3 years 8 months ago
The Dfam database of repetitive DNA families
Repetitive DNA, especially that due to transposable elements (TEs), makes up a large fraction of many genomes. Dfam is an open access database of families of repetitive DNA elemen...
Robert Hubley, Robert D. Finn, Jody Clements, Sean...
NAR
2016
36views more  NAR 2016»
3 years 8 months ago
DriverDBv2: a database for human cancer driver gene research
We previously presented DriverDB, a database that incorporates ∼6000 cases of exome-seq data, in addition to annotation databases and published bioinformatics algorithms dedicat...
I-Fang Chung, Chen-Yang Chen, Shih-Chieh Su, Chia-...
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