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BMCBI
2010
114views more  BMCBI 2010»
14 years 11 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2008
228views more  BMCBI 2008»
14 years 11 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
AAAI
2006
15 years 1 months ago
Multi-Conditional Learning: Generative/Discriminative Training for Clustering and Classification
This paper presents multi-conditional learning (MCL), a training criterion based on a product of multiple conditional likelihoods. When combining the traditional conditional proba...
Andrew McCallum, Chris Pal, Gregory Druck, Xuerui ...
SSPR
2004
Springer
15 years 5 months ago
Optimizing Classification Ensembles via a Genetic Algorithm for a Web-Based Educational System
Classification fusion combines multiple classifications of data into a single classification solution of greater accuracy. Feature extraction aims to reduce the computational cost ...
Behrouz Minaei-Bidgoli, Gerd Kortemeyer, William F...
BMCBI
2008
114views more  BMCBI 2008»
14 years 11 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl