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» Computing with Evolving Proteins
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BMCBI
2002
126views more  BMCBI 2002»
14 years 10 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
JCB
2002
116views more  JCB 2002»
14 years 10 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
NAR
2010
281views more  NAR 2010»
14 years 5 months ago
PDBselect 1992-2009 and PDBfilter-select
PDBselect (http://bioinfo.tg.fh-giessen.de/pdb select/) is a list of representative protein chains with low mutual sequence identity selected from the protein data bank (PDB) to e...
Sven Griep, Uwe Hobohm
BMCBI
2011
14 years 2 months ago
In-silico prediction of disorder content using hybrid sequence representation
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
NAR
2011
209views Computer Vision» more  NAR 2011»
14 years 1 months ago
REPAIRtoire - a database of DNA repair pathways
REPAIRtoire is the first comprehensive database resource for systems biology of DNA damage and repair. The database collects and organizes the following types of information: (i) ...
Kaja Milanowska, Joanna Krwawicz, Grzegorz Papaj, ...