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BMCBI
2007
163views more  BMCBI 2007»
14 years 11 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2005
113views more  BMCBI 2005»
14 years 11 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2006
146views more  BMCBI 2006»
14 years 12 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
CSB
2004
IEEE
136views Bioinformatics» more  CSB 2004»
15 years 3 months ago
Minimum Entropy Clustering and Applications to Gene Expression Analysis
Clustering is a common methodology for analyzing the gene expression data. In this paper, we present a new clustering algorithm from an information-theoretic point of view. First,...
Haifeng Li, Keshu Zhang, Tao Jiang
BMCBI
2008
166views more  BMCBI 2008»
14 years 12 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf