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BIOCOMP
2008
15 years 1 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2006
87views more  BMCBI 2006»
14 years 12 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2010
153views more  BMCBI 2010»
14 years 12 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
BMCBI
2007
130views more  BMCBI 2007»
14 years 12 months ago
A robust measure of correlation between two genes on a microarray
Background: The underlying goal of microarray experiments is to identify gene expression patterns across different experimental conditions. Genes that are contained in a particula...
Johanna S. Hardin, Aya Mitani, Leanne Hicks, Brian...
BIOINFORMATICS
2004
99views more  BIOINFORMATICS 2004»
14 years 11 months ago
EST clustering error evaluation and correction
Motivation: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, James Leeb...