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BMCBI
2010
115views more  BMCBI 2010»
14 years 12 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
139views more  BMCBI 2010»
14 years 12 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
ISDA
2008
IEEE
15 years 6 months ago
Combining Clustering and Bayesian Network for Gene Network Inference
Gene network reconstruction is a multidisciplinary research area involving data mining, machine learning, statistics, ontologies and others. Reconstructed gene network allows us t...
Suhaila Zainudin, Safaai Deris
BMCBI
2008
115views more  BMCBI 2008»
14 years 12 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2007
111views more  BMCBI 2007»
14 years 11 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda