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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
14 years 12 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMCBI
2010
113views more  BMCBI 2010»
14 years 12 months ago
Gene prioritization and clustering by multi-view text mining
Background: Text mining has become a useful tool for biologists trying to understand the genetics of diseases. In particular, it can help identify the most interesting candidate g...
Shi Yu, Léon-Charles Tranchevent, Bart De M...
BMCBI
2010
183views more  BMCBI 2010»
14 years 12 months ago
SING: Subgraph search In Non-homogeneous Graphs
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
Raffaele Di Natale, Alfredo Ferro, Rosalba Giugno,...
BMCBI
2007
135views more  BMCBI 2007»
14 years 12 months ago
RECOVIR: An application package to automatically identify some single stranded RNA viruses using capsid protein residues that un
Background: Most single stranded RNA (ssRNA) viruses mutate rapidly to generate large number of strains having highly divergent capsid sequences. Accurate strain recognition in un...
Dianhui Zhu, George E. Fox, Sugoto Chakravarty
BMCBI
2008
123views more  BMCBI 2008»
14 years 12 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...