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BMCBI
2008
211views more  BMCBI 2008»
15 years 5 months ago
CPSP-tools - Exact and complete algorithms for high-throughput 3D lattice protein studies
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
Martin Mann, Sebastian Will, Rolf Backofen
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 5 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BMCBI
2007
59views more  BMCBI 2007»
15 years 5 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis
JMLR
2008
168views more  JMLR 2008»
15 years 5 months ago
Max-margin Classification of Data with Absent Features
We consider the problem of learning classifiers in structured domains, where some objects have a subset of features that are inherently absent due to complex relationships between...
Gal Chechik, Geremy Heitz, Gal Elidan, Pieter Abbe...
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NAR
2006
87views more  NAR 2006»
15 years 5 months ago
From genomics to chemical genomics: new developments in KEGG
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interacti...
Minoru Kanehisa, Susumu Goto, Masahiro Hattori, Ki...