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» Three lectures on case-control genetic association analysis
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BIB
2008
82views more  BIB 2008»
13 years 7 months ago
Three lectures on case-control genetic association analysis
The purpose of this review is to focus on the three most important themes in genetic association studies using randomly selected patients (case, affected) and normal samples (cont...
Wentian Li
23
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BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...
BMCBI
2005
157views more  BMCBI 2005»
13 years 7 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
BMCBI
2010
161views more  BMCBI 2010»
13 years 4 months ago
Application of Wavelet Packet Transform to detect genetic polymorphisms by the analysis of inter-Alu PCR patterns
Background: The analysis of Inter-Alu PCR patterns obtained from human genomic DNA samples is a promising technique for a simultaneous analysis of many genomic loci flanked by Alu...
Maurizio Cardelli, Matteo Nicoli, Armando Bazzani,...
21
Voted
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris