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BMCBI
2010
14 years 11 months ago
2010
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
118
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BMCBI
2010
14 years 11 months ago
2010
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
BMCBI
2010
14 years 11 months ago
2010
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
100
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BMCBI
2010
14 years 11 months ago
2010
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
118
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BMCBI
2010
14 years 11 months ago
2010
Background: Overlapping genes (OGs) are defined as adjacent genes whose coding sequences overlap partially or entirely. In fact, they are ubiquitous in microbial genomes and more ...