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CPM
2010
Springer

Mod/Resc Parsimony Inference

14 years 3 months ago
Mod/Resc Parsimony Inference
Abstract. We address in this paper a new computational biology problem that aims at understanding a mechanism that could potentially be used to genetically manipulate natural insect populations infected by inherited, intra-cellular parasitic bacteria. In this problem, that we denote by Mod/Resc Parsimony Inference, we are given a boolean matrix and the goal is to find two other boolean matrices with a minimum number of columns such that an appropriately defined operation on these matrices gives back the input. We show that this is formally equivalent to the Bipartite Biclique Edge Cover problem and derive some complexity results for our problem using this equivalence. We provide a new, fixed-parameter tractability approach for solving both that slightly improves upon a previously published algorithm for the Bipartite Biclique Edge Cover. Finally, we present experimental results where we applied some of our techniques to a real-life data set.
Igor Nor, Danny Hermelin, Sylvain Charlat, Jan Eng
Added 19 Jul 2010
Updated 19 Jul 2010
Type Conference
Year 2010
Where CPM
Authors Igor Nor, Danny Hermelin, Sylvain Charlat, Jan Engelstadter, Max Reuter, Olivier Duron, Marie-France Sagot
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