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2006

Classifying protein sequences using hydropathy blocks

8 years 10 months ago
Classifying protein sequences using hydropathy blocks
The annotation of proteins can be achieved by classifying the protein of interest into a certain known protein family to induce its functional and structural features. This paper presents a new method for classifying protein sequences based upon the hydropathy blocks occurring in protein sequences. First, a fixed-dimensional feature vector is generated for each protein sequence using the frequency of the hydropathy blocks occurring in the sequence. Then, the support vector machine (SVM) classifier is utilized to classify the protein sequences into the known protein families. The experimental results have shown that the proteins belonging to the same family or subfamily can be identified using features generated from the hydropathy blocks. 2005 Pattern Recognition Society. Published by Elsevier Ltd. All rights reserved.
De-Shuang Huang, Xing-Ming Zhao, Guang-Bin Huang,
Added 14 Dec 2010
Updated 14 Dec 2010
Type Journal
Year 2006
Where PR
Authors De-Shuang Huang, Xing-Ming Zhao, Guang-Bin Huang, Yiu-ming Cheung
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