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NAR
2011

DIMA 3.0: Domain Interaction Map

7 years 9 months ago
DIMA 3.0: Domain Interaction Map
Domain Interaction MAp (DIMA, available at http:// webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 structurally known interactions imported from the iPfam and 3did databases and 46 900 domain interactions predicted by four computational methods: domain phylogenetic profiling, domain pair exclusion algorithm correlated mutations and domain interaction prediction in a discriminative way. Additionally predictions are filtered to exclude those domain pairs that are reported as non-interacting by the Negatome database. The DIMA Web site allows to calculate domain interaction networks either for a domain of interest or for entire organisms, and to explore them interactively using the Flash-based Cytoscape Web software.
Qibin Luo, Philipp Pagel, Baiba Vilne, Dmitrij Fri
Added 16 Sep 2011
Updated 16 Sep 2011
Type Journal
Year 2011
Where NAR
Authors Qibin Luo, Philipp Pagel, Baiba Vilne, Dmitrij Frishman
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