Efficient Boolean implementation of universal sequence maps (bUSM)

11 years 5 months ago
Efficient Boolean implementation of universal sequence maps (bUSM)
Background: Recently, Almeida and Vinga offered a new approach for the representation of arbitrary discrete sequences, referred to as Universal Sequence Maps (USM), and discussed its applicability to genomic sequence analysis. Their work generalizes and extends Chaos Game Representation (CGR) of DNA for arbitrary discrete sequences. Results: We have considered issues associated with the practical implementation of USMs and offer a variation on the algorithm that: 1) eliminates the overestimation of similar segment lengths, 2) permits the identification of arbitrarily long similar segments in the context of finite word length coordinate representations, 3) uses more computationally efficient operations, and 4) provides a simple conversion for recovering the USM coordinates. Computational performance comparisons and examples are provided. Conclusions: We have shown that the desirable properties of the USM encoding of nucleotide sequences can be retained in a practical implementation of ...
John Schwacke, Jonas S. Almeida
Added 17 Dec 2010
Updated 17 Dec 2010
Type Journal
Year 2002
Authors John Schwacke, Jonas S. Almeida
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