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BMCBI
2004

Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms

10 years 2 months ago
Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms
Background: Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein subcellular location is urgently needed. Results: Esub8 was developed to predict protein subcellular localizations for eukaryotic proteins based on amino acid composition. In this research, the proteins are classified into the following eight groups: chloroplast, cytoplasm, extracellular, Golgi apparatus, lysosome, mitochondria, nucleus and peroxisome. We know subcellular localization is a typical classification problem; consequently, a one-against-one (1-v-1) multi-class support vector machine was introduced to construct the classifier. Unlike previous methods, ours considers the order information of protein sequences by a different method. Our method is tested in three subcellular localization predictions for prokaryotic proteins and f...
Qinghua Cui, Tianzi Jiang, Bing Liu, Songde Ma
Added 16 Dec 2010
Updated 16 Dec 2010
Type Journal
Year 2004
Where BMCBI
Authors Qinghua Cui, Tianzi Jiang, Bing Liu, Songde Ma
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