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2007

FLAN: a web server for influenza virus genome annotation

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FLAN: a web server for influenza virus genome annotation
FLAN (short for FLu ANnotation), the NCBI web server for genome annotation of influenza virus (http://www.ncbi.nlm.nih.gov/genomes/FLU/ Database/annotation.cgi) is a tool for user-provided influenza A virus or influenza B virus sequences. It can validate and predict protein sequences encoded by an input flu sequence. The input sequence is BLASTed against a database containing influenza sequences to determine the virus type (A or B), segment (1 through 8) and subtype for the hemagglutinin and neuraminidase segments of influenza A virus. For each segment/subtype of the viruses, a set of sample protein sequences is maintained. The input sequence is then aligned against the corresponding protein set with a ‘Protein to nucleotide alignment tool’ (ProSplign). The translated product from the best alignment to the sample protein sequence is used as the predicted protein encoded by the input sequence. The output can be a feature table that can be used for sequence submission to GenBank (by...
Yiming Bao, Pavel Bolotov, Dmitry Dernovoy, Boris
Added 27 Dec 2010
Updated 27 Dec 2010
Type Journal
Year 2007
Where NAR
Authors Yiming Bao, Pavel Bolotov, Dmitry Dernovoy, Boris Kiryutin, Tatiana A. Tatusova
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